Alfuzosin XL (alfuzosin hydrochloride) is an alpha blocker used to alleviate symptoms of benign prostatic hyperplasia (BPH), better known as an enlarged prostate.

The XL in this product's name indicates it is an extended-release version; Alfuzosin XL is taken just once per day, compared to immediate-release tablets which are taken two or three times per day.

Alfuzosin XL works by relaxing the muscles in the prostate and around the bladder and urethra, making urine easier to pass. This action usually significantly alleviates the symptoms of BPH, including:

• Difficulty urinating
• Weak urine stream
• Urgent urination
• Frequent urination
• Waking up several times to urinate
• Excessive dribbling at the end of urination
• Inability to fully empty the bladder

Results do vary to some extent; some men will have complete relief with treatment, while others will experience only a reduction of symptoms. If the medication does not satisfactorily resolve the problem speak with a doctor about alternative options.

What Alfuzosin XL does not do is influence prostate size; it is not a cure for BPH and will not slow, stop, or shrink the prostate. Other medications that do so may be given along with Alfuzosin XL.

How to Take Alfuzosin XL

Alfuzosin XL comes in tablets, which must be swallowed whole and taken with food. Destroying the integrity of tablets by splitting, chewing, crushing and so forth will ruin its extended-release properties. Absorption of the tablets is increased when taken with food.

Though taken just once per day, taking each tablet at the same time each day is also recommended, to keep levels of the medication steady in the body.

For the majority of men:

• Take 10 mg (one tablet) once per day.
• Tablets should be taken with food.
• Treatment may continue for as long as needed.

Men who have, or are at great risk of developing, other major medical conditions may need adjusted doses. In most cases this will mean switching to immediate-release tablets, which are taken more frequently but are available in lower doses.

Most men notice some improvement in symptoms just days after starting use, but it can take up to a month before full benefit is seen. Give the medication at least a month, assuming no serious adverse effects develop, before deciding it doesn't work.

If BPH has not otherwise been addressed, ending treatment with Alfuzosin XL will most likely cause symptoms to return.

Other Uses

BPH is largely a condition found in older men, so there is little use for this medication in young men or women. As a general rule young men and women should not take Alfuzosin XL.

There are some rare exceptions, however. Alfuzosin XL is sometimes used to help pass bladder stones, for example. If taking this medication for an unusual use be sure to follow doctor instructions regarding dosage, frequency, and duration of treatment; the above instructions may not apply.

Other Concerns

Men who use Alfuzosin XL as directed usually do not experience any serious side effects, with one exception: blood pressure. Alfuzosin XL will lower blood pressure to some extent, though the medication is not used as a hypertension treatment.

Even if blood pressure stays within normal ranges, a drop can cause symptoms. These symptoms, if they occur, nearly always take place at the start of treatment and stop occurring after the first few weeks, as the body adjusts to its new, lower blood pressure.

Symptoms of low blood pressure include:

• Dizziness
• Fatigue
• Blurry vision
• Nausea
• Clammy skin
• Fainting

In the vast majority of cases the above symptoms are mild and not cause for concern. If any become severe, or if fainting is experienced, speak with a doctor.

Use caution when performing dangerous tasks until effects are known or symptoms stop occurring. Consuming alcohol can significantly worsen symptoms.

Men taking medications to lower blood pressure should be sure the prescribing doctor is aware, and should be alert for low blood pressure symptoms when starting Alfuzosin XL.

Men who have preexisting low blood pressure are poor candidates for this medication. A doctor may be able to suggest alternative treatments.