Bactroban Ointment (mupirocin) is an RNA sythetase inhibitor used for the localized, topical treatment of impetigo and certain other superficial Staphylococcus skin infections. It works by interfering with protein synthesis in the target bacteria, depriving it of the conditions it needs to survive.

Bactroban Ointment is unlikely to be effective in the treatment of infections resulting from bacteria other than Staphylococcus. Use for longer than 10 consecutive days is generally not recommended due to concerns that the bacteria may develop resistance to the medication.

Getting Started with Bactroban Ointment

Bactroban ointment is for topical use only; it should not be ingested or applied directly to mucous membranes.

For best results a doctor should identify the bacteria causing the infection, and doctor instructions should be followed for the full course of treatment even if the condition appears to clear up. Likewise do not use for longer than recommended. Ending treatment early or continuing it longer can result in reinfection with antibiotic resistant bacteria, which will be considerably more difficult to treat.

Administration is simple:

• Apply a dab of the ointment to the target area three times per day.
• A breathable bandage may be applied over the treatment if desired.
• Do not use longer than ten consecutive days unless explicitly instructed to do so by a doctor.
• Do not use Bactroban Ointment with other topical treatments unless specifically instructed do so by a doctor.

If treating impetigo keep in mind that the conditions is contagious and easily spread. Wash hands thoroughly after each application and carefully dispose of any used dressings or other materials that have contacted the infected area.

Patients may experience some relief of symptoms, such as tenderness, itching, or inflammation, within moments of the first application. The condition should be noticeably improved within 5 days of starting treatment. If there are no significant improvements within this time frame a doctor should be consulted; alternative treatments will likely be required. Unresponsive conditions may be due to incorrectly identified bacteria or a strain that has already developed resistance to mupirocin.

Potential Side Effects

Rarely some patients experience an allergic reaction to Bactroban Ointment, which should be considered a medical emergency. Warning signs include:

• Difficulty breathing
• Swelling of face and/or throat
• Rapid or erratic heartbeat
• Dizziness
• Hives, rash, or severe itching

Most people experience only mild side effects localized to the application site; these symptoms aren't cause for concern unless they become severe:

• Stinging
• Mild pain
• Mild itching

The above symptoms typically occur only when the ointment is first applied and fade away after a few moments.

Unfortunately some patients experience more severe adverse reactions from Bactroban Ointment. Consult a doctor if:

• The infection worsens or spreads during treatment
• Skin begins to peel or blister at application site
• New skin infections develop, even if seemingly unrelated
• Any other moderate to severe irritation develop around application site

Because Bactroban Ointment is topical, interactions with orally-administered medications are unlikely. The medication should not applied to mucous membranes or open wounds. If the medication is ingested by children or pets seek emergency medical advice.

Topical treatments are rarely present in the bloodstream in quantities high enough to be harmful, but parents may want to discuss potential risks with a doctor before use.