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Azor HCT (amlodipine, olmesartan, hydrochlorothiazide), also known as Sevikar HCT, is a hypertension treatment meant for individuals who have high blood pressure. This product contains three active ingredients, each of which can be used individually to manage high blood pressure but which produce more powerful---and convenient---results when combined in a single tablet.

The three ingredients in this product are:

• Amlodipine is a a calcium channel blocker that relaxes muscles in the heart and those that tighten and narrow blood vessels.
• Olmesartan is an angiotensin-2 receptor antagonist that blocks the naturally-occurring angiotensin II. Angiotensin II further encourages blood vessels to narrow and tighten; olmesartan does the opposite.
• Hydrochlorothiazide is a diuretic which works by encouraging the kidneys to get rid of unneeded water and salt from the body, passed out in urine.

Not every patient needs such a potent medication, however; one can also buy Azor, containing just amlodipine and olmesartan, or just amlodipine, just olmesartan, or just hydrochlorothiazide. There are also numerous other combinations of similar products available.

Taking Control of Blood Pressure with Azor HCT

Patients can take Azor HCT to combine three separate medications being taken, or may be prescribed Azor HCT from the start when multiple medications are likely needed. Black patients, which are more resistant to hypertension medications---the medications produce minimal results---are more likely than other races to initially start treatment with multiple medications.

The medications come in tablets, which should be swallowed whole. Food is optional, though taking with a glass of fluid is preferred. It will take about two weeks of treatment for full effects, either from the start of treatment or following dosage adjustments, to be felt. Dosage adjustments should not be made prior to a week, preferably two weeks, after starting treatment.

Patients are usually started on lower doses, which may be increased if effects are insignificant. Other medications, other medical conditions, and personable variables like age and weight might also influence dosage.

Treatment may continue indefinitely, often for the remainder of life if lifestyle changes are not made or are not sufficient to control blood pressure. Such changes include exercise, stopping smoking, controlling cholesterol and blood sugar, and so forth. A small percentage of patients have high blood pressure despite otherwise being in great health, in which case there's not a lot that can be done.

Side Effects & Complications

Side effects from Azor HCT are relatively rare, but do happen. Most commonly reported are:

• Dizziness
• Drowsiness
• Flushing
• Hair loss
• Mild rash or itching

The diuretic in Azor HCT can influence electrolyte levels, particularly potassium in the blood. These levels may need to be monitored.

Azor HCT is meant to lower blood pressure, and can produce a range of related symptoms. Patients may feel weak, and may feel especially lightheaded if rising from a sitting or laying position quickly. These symptoms aren't cause for concern unless severe, and should pass with the first week or two of treatment.

More rarely serious side effects develop, which call for medical attention:

• Passing out
• Pounding or fluttering heartbeat
• Rapid weight gain
• Edema in hands or feet
• Urinating less than usual
• Jaundice

Very rarely Azor HCT can cause a breakdown of skeletal muscle tissue, which can ultimately lead to kidney failure. Patients should be alert for muscle tenderness, pain, or weakness, particularly if unexplained and accompanied by fever and dark-colored urine. If this happens, seek medical attention.

Effects of Azor HCT on unborn or nursing babies are unclear; women who are pregnant or breastfeeding should speak with a doctor.