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Femoston Conti Low (estradiol, dydrogesterone) is a lightweight hormone replacement therapy (HRT) for postmenopausal women with an intact uterus. Each tablet contains 0.5 mg estradiol and 2.5 mg dydrogesterone.

Both ingredients in this product are primary female sex hormones, responsible for the development and maintenance of female characteristics and the reproductive system. Production of these hormones declines naturally with age, reaching their low point with menopause. This can produce a range of unpleasant symptoms:

• Dry skin
• Thinning hair
• Hot flashes
• Night sweats
• Chills
• Irritability
• Sleep disruptions
• Vaginal dryness
• Painful intercourse
• Loss of breast fullness

After 2 to 4 weeks of taking Femoston Conti Low the above symptoms will begin to improve.

Femoston Conti Low also prevents loss of bone mineral density, and may be used by women at risk of bone loss even when other menopause symptoms aren't present or aren't especially bothersome. However, higher strengths of the medication found in regular Femoston Conti may be preferred.

Who Uses HRT

Femoston Conti Low is meant for postmenopausal women who have an intact uterus, and who are experiencing menopause symptoms severe enough to be disruptive to daily life. This can also apply to younger women who have had their hormones disrupted through surgery, medications, or injury.

It's actually the estradiol in Femoston Conti Low that relieves menopause symptoms; the progestin---dydrogesterone---is added to protect the uterus from side effects of estrogen, such as endometrial cancer, though it does produce mild benefits as well. Women who have had their uterus removed do not need to take a progesterone/progestin, and can make use of estrogen-only treatment. Estrogen-only treatments and other combinations of estrogen with a progestin can be browsed here.

In all cases Femoston Conti Low---or any HRT---should be taken at the lowest effective dose and for the shortest possible time. The need to continue HRT should be reassessed every six months. Continued, long-term use of HRT can produce serious side effects, particularly in women with other medical conditions present.

How to Use Femoston Conti Low

Femoston Conti Low is the lowest possible dose of Femoston Conti. It may be given as a starter dose, increased after several weeks to regular Femoston Conti strengths, or it may prove suitable on its own. The Low version of the product in particular may be given to women who are at relatively high risk of experiencing adverse reactions from higher doses.

Regardless of which strength of the medication is being taken, dosage is the same:

• Take one tablet once per day.
• Food is optional; fluid is recommended.
• Take tablets at the same time each day.

Brand-name Femoston Conti Low comes in blister packs with each day of the month marked to help patients keep track. Generic versions may vary. There should be no gaps in taking tablets---once per day, every day. Occasionally one may be missed; skip it entirely and resume treatment with the next dose.

Treatment may continue for 6 months to several years, provided no side effects develop.

Potential Complications

Patients taking estrogen HRT are at a slightly increased risk of breast cancer, other estrogen-dependent tumors, blood clots, heart attack, and stroke. This risk goes up with the duration of use of estrogen HRT, and is further complicated when the women taking it are already at risk for those factors.

Women with the following should generally avoid Femoston Conti Low:

• Breast cancer/history of breast cancer
• Estrogen-dependent tumors
• Porphyria
• Untreated endometrial hyperplasia
• Blood clots/history of blood clots
• Liver disease
• Cardiovascular issues

Other, more common side effects are much milder and generally not cause for concern. They're usually transient, as well, meaning they'll stop occurring after the first few weeks of treatment. Common side effects are:

• Headache (not migraine)
• Spotting
• Vaginal discharge
• Tender breasts
• Gastrointestinal symptoms

Rarely more serious side effects develop, which call for discontinuation of Femoston Conti Low:

• Jaundice or other symptoms of liver impairment
• New migraine headaches
• Significant increase in blood pressure

Femoston Conti Low can interact with other treatments, particularly other estrogen- and/or progestin-containing medications. Speak with a doctor or pharmacist before mixing medications.