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Imigran Nasal Spray (sumatriptan succinate) is a potent triptan medication used to stop migraines and cluster headaches. It is an abortive treatment, meaning it only stops headaches in progress; it provides no benefit in preventing new headaches from forming if taken when a headache is not occurring.

Like all triptan medications, Imigran Nasal Spray works by narrowing blood vessels in the head. During migraine or cluster headache episodes blood vessels on the surface of the brain become swollen; while this is not the only change that occurs and may not be the only factor contributing to pain, it has become clear through decades of widespread triptan use that the narrowing of these blood vessels significantly alleviates or eliminates pain during these types of headaches. Auras and other symptoms associated with migraines, such as light sensitivity and nausea, are also often alleviated. Because of the way this medication works---it is not a painkiller---it will have no impact on other types of headaches, such as tension or sinus headaches.

Using Imigran Nasal Spray

Imigran Nasal Spray is available in two strengths; 10 mg and 20 mg. This is how much medication is delivered in each dose (spray). The standard dose that most patients use is 20 mg, though some find 10 mg sufficient. The lowest effective dose is preferred, as risk of side effects does increase with higher doses.

The medication is easy to use:

• Administer one dose at the earliest symptoms a headache is developing.
• If symptoms return, an additional dose may be administered as long as there is at least two hours between doses.
• Do not exceed 40 mg of Imigran Nasal Spray in a 24 hour period.

Effects start to be felt about 15 minutes after administration. It is not unusual for other medications, such as traditional painkillers like ibuprofen or other NSAIDs, to be taken along with triptan medications during a headache episode. Patients are strongly advised to check with a doctor before doing so, particularly if there are any major medical conditions present.

Other Imigran Options

Imigran is available in a variety of formulations. Cluster headache-sufferers in particular should pay attention to the speed at which the medication begins to work; this is often a critical factor in effectiveness.

• Imigran Tablets - the slowest-acting form of the medication, effects are felt about 30 minutes after administration. Tablets are generally not the best choice for most cluster headache-sufferers.
• Imigran Radis - these tablets are designed to be dissolved in fluids. Effects are felt slightly faster than regular tablets. Ideal for patients who have difficulty swallowing whole tablets, though it will taste bitter.
• Imigran Subject Injection - the fastest-acting formula, effects are felt in 5 to 10 minutes. Ideal for cluster headaches or severe migraines. Injections are delivered subcutaneously (just beneath the skin) rather than into muscle or veins; the small, fine needles used are virtually painless.

Dosage and administration instructions will vary by formulation; be sure to read the insert included with each product.

Before Using Imigran

Most people use Imigran Nasal Spray with no problems; some patients do experience mild side effects, but the alleviation of pain usually compensates. There are, however, some risk factors that put patients at higher risk of experiencing serious side effects. This product should not be used without doctor approval if there is a history of:

• Heart problems, angina or stroke
• Vascular disease or poor blood circulation
• Liver or kidney impairment
• Severe or untreated hypertension

Imigran Nasal Spray can interact with other medications. In particular triptan medications like this product should not be used within a week of taking SSRI, SNRI, or MAOI medications (usually prescribed to treat anxiety, depression and similar mental conditions). If in doubt, check with a doctor or pharmacist before mixing medications.