Persantine

Strokes, heart attacks, and pulmonary embolisms are all serious complications of clots. Antiplatelet drug Persantine works by inhibiting platelets. Blood vessels in the heart remain open, and platelets do not clump together as a result. As a blood clot preventative, Persantine, also known as dipyridamole, is used after heart valve surgery.

How does Persantine work?

After heart valve replacement, blood clots could occur. This medication prevents them. The blood cell type called platelet cannot stick together following treatment with Persantine. Also, this medication is used in tests that measure the flow of blood in the heart.

Persantine may be sold under more than one brand name and in more than one form. Not all the conditions discussed here may be treated with every brand name of this medication. Doctors may suggest this medication for conditions other than those listed here.

If patients do not know why they are taking this medication or have not discussed it with their doctor, they should contact a physician ASAP. Similarly, doctors should be consulted before stopping this medication.

Persantine Alternatives

• Aspirin: Aspirin is both a pain killer and a blood thinner.
• Warfarin: Warfarin is another commonly prescribed blood thinner.

How to use Persantine

Patients must follow the doctor's instructions when taking this medication. The dosage prescribed varies based on the patient's medical condition and treatment response. One can benefit the most from this medication if one takes it regularly. One way to take it consistently is to set reminders and alarms. 

Dosage

Persantine is typically administered at a dose of 75-100 mg four times a day to treat blood clots after heart valve replacement. 

In preventing postoperative thromboembolic complications after heart valve replacement, Persantine tablets can be used together with anticoagulants such as coumarin.

Common side effects of Persantine include:

• Stomach upset
• Dizziness
• Diarrhea
• Precautions
• Headache
• Vomiting
• Flushing

Who can take Persantine?

Dipyridamole can be taken by adults 18 and older as a stroke prevention drug and after contracting a heart attack and requiring a valve replacement.

Children with Kawasaki disease or those who have had heart surgery are sometimes given this medication.

Who cannot take Persantine?

• Those with angina and heart problems
• Those that are allergic to Persantine
• People with hemophilia
• People with low blood pressure

Precautions

If patients have allergies, they should tell the doctor or pharmacist before taking dipyridamole. There is a chance that this product contains ingredients that can cause allergic reactions. More information can be obtained from a pharmacist.

Patients must tell their physician or pharmacist about any medical problems they have had in the past, such as heart problems, coronary artery disease, recent cardiovascular illness, high blood pressure, liver disease, and problems with muscles (myasthenia gravis).

This drug may cause dizziness. This may worsen if patients use it with alcohol or marijuana (cannabis). Doctors recommend that patients avoid driving, using machinery, or any other activity that requires alertness when on this medication.

Further, before prescription, patients must disclose to the doctor or dentist about any medications or herbal products they may be using (including prescription and OTC  products).

The use of this medication during pregnancy should be limited to those required. Depending on the benefits versus risks, doctors may choose to prescribe it anyway.

Breastfeeding is possible while taking this medication, but it should only be done after consulting a doctor.

Interactions

Patients may experience side effects or even encounter changes in how the medication works due to drug interactions. One must keep a list of all the products they use and share it with their doctor and pharmacist. If one plans to stop taking medicine or change, they should first notify their doctor.

The interaction between this medication and Riociguat and some antiplatelet medications (such as abciximab and ticlopidine) is not known. The doctor can assess the aspirin compatibility of this medication if patients are currently taking it.

Those who are not currently taking aspirin should consult their doctor before starting. Other medications that could cause bleeding may be taken with this medication.

Several blood thinners (such as warfarin and heparin) are examples of this class of drugs. Taking this medication can interfere with certain medical tests (such as chemical stress tests using Adenosine or Dipyridamole) and may result in false positives.

Patients must consult their doctor or pharmacist before taking this medication. In the event of unusual bleeding, patients should notify their doctor immediately.

Storage

Light and moisture should not be present in the storage area—store at room temperature. The bathroom is not a good place to store Persantine. Unless instructed otherwise, children and pets should not be exposed to medications. Failure to follow doctors' instructions can lead to a medical emergency. The product should be disposed of properly when it has expired or no longer serves its intended purpose. For disposal of waste, patients can contact their pharmacist.

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