Victoza (liraglutide) is an injectable medication used to help manage blood glucose levels in type 2 diabetes. Note that this product requires refrigeration.

Victoza is an interesting treatment; it is a Recombinant DNA (rDNA) origin medication, based on molecules developed in a laboratory by recombining genetic materials in new ways. In technical terms it is a derivative of the metabolic hormone human incretin glucagon-like peptide-1 (GLP-1) that acts as a GLP-1 receptor agonist. In simpler terms, Victoza binds to receptors which increase production of insulin in the pancreas, while inhibiting production of the competing hormone glucagon.

This medication is generally prescribed only to patients who have demonstrated a commitment to adopting lifestyle changes. Victoza helps reduce the need for insulin therapy and promotes natural insulin production while patients continue to improve overall health, until medications are no longer needed at all.

In the interim, lowering blood glucose can slow or halt progression of diabetic symptoms, resulting in improved quality of life and preventing catastrophic complications.

The active ingredient in this medication, liraglutide, is also marketed as a weight-loss drug under the brand name Saxenda. For more information on this application please see our liraglutide page.

How to Take Victoza

Victoza is delivered via subcutaneous injection; the product comes in injection pens for easy and convenient administration. Each pen contains multiple doses and can be adjusted to deliver doses of 0.6 mg, 1.2 mg, or 1.8 mg. Tips for the pens are also included; tips have very thin, fine needles for virtually painless administration.

General administration guidelines are as follows:

• Inspect the solution in the pen prior to each use and only use if clear and free of particulates.
• Administer to clean, dry skin on the abdomen, thigh, or upper arm.
• Do not administer at the exact same site as an insulin injection.
• Injections should be administered once per day.
• Most patients are started on 0.6 mg for one week.
• After one week, if no adverse effects develop, dosage may increase to 1.2 mg per day.
• After another week, assuming no adverse effects, dosage may increase to 1.8 mg per day.
• Do not exceed 1.8 mg per day.
• If treatment is stopped for 3 or more days, restart treatment at 0.6 mg.
• Always use a new needle for each injection to prevent contamination or infection.

Blood glucose should be monitored carefully at the start of treatment and following any dosage adjustments, especially if other diabetic medications are being taken.

Dosage of Victoza is largely dependent upon the preexisting level of kidney function; kidney function should be evaluated prior to starting treatment and regularly for the duration of treatment. A physician is best prepared to properly evaluate kidney function with appropriate tests such as Blood Urea Nitrogen and Estimated Glomerular Filtration Rate.

Regular doctor checkups will also permit screening for other potentially-developing side effects.

Potential Complications

Since Victoza lowers blood glucose levels, symptoms of low blood glucose can result. Victoza is among the less-likely medications to cause dangerously low drops in blood glucose, however; while such incidence resulting from the use of sulfonuric drugs is about 25%, the incidence with Victoza is only about 5%. This risk is considerably increased if other blood glucose-lowering medications are being taken, however; patients should be alert for symptoms of hypoglycemia and be prepared to handle it should it arise.

The most common side effects associated with this medication are scratchy nose or throat and mild respiratory symptoms comparable to those experienced with the common cold.

Because Victoza causes an increase in stomach emptying time, those who already have issues with delayed gastric emptying should consider alternate therapies.

Studies have shown a risk of thyroid C-cell tumors in rats given Victoza. No causal relationship in humans has been established; it is unknown if this is a risk, but regular screenings for abnormalities are advisable.

There is also a slight association with pancreatitis, an inflammation of the pancreas, while taking Victoza. This, too, can be caught and handled early with regular checkups.

As mentioned above, Victoza causes a delay in stomach emptying. This may cause increased absorption of other medications administered by mouth. Check with a doctor or pharmacist about taking other medications along with Victoza.

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What Is Saxenda?

Also known as "liraglutide," Saxenda is a drug that mimics a naturally occurring hormone in your body. This can help control everything from:

• Your blood sugar levels
• Your insulin levels
• Your digestion levels

In addition to this, Saxenda is a prescription that you can inject directly into your system, which may be helpful for overweight or obese adults. Not to mention that injectable prescriptions like Saxenda could be an ideal solution for other weight loss problems. Besides this, youths under the age of 17 years old with an above-average body weight may also be prescribed Saxenda.

That being said, Saxenda should never be prescribed to those who suffer from type one diabetes or type two diabetes. Also, it's important to know that Saxenda isn't distributed as an appetite suppressant or a weight loss medication either.

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Saxenda Safety Precautions

For those of you who were unaware, Saxenda manufactured by Victoza may be prescribed along with exercise and diet to treat certain forms of diabetes. We highly recommend that you avoid using Victoza and Saxenda at the same time. Additionally, you might want to avoid using Saxenda if you are dealing with:

• Multiple endocrine neoplasia type 2
• Medullary thyroid cancer
• Insulin-dependent diabetes
• Diabetic ketoacidosis
• Pregnancy

Besides this, we suggest that you talk to your physician if you've ever shown symptoms of thyroid tumors. This includes signs such as shortness of breath, hoarse voice, neck swelling or lumps, and overall swelling.

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Precautions Before Trying Saxenda  

If you have ever suffered from an allergic reaction to Saxenda, you might not want to continue taking this prescription. The same recommendation applies to those who have:

• A family history of gland tumors
• A family history of thyroid cancer
• A family history of diabetic ketoacidosis

Also, you may want to avoid using Saxenda if you are taking insulin medications or other prescriptions such as Trulicity, Tanzeum, Bydureon, Byetta, exenatide, dulaglutide, albiglutide.

If you're not sure if Saxenda is the perfect prescription, talk to your physician if you suffer from:

• A personal history of suicidal thoughts or depression
• A personal history of gallbladder or pancreas problems
• A personal history of heart issues
• A personal history of hyper triglycerides

Because research hasn't shown whether or not using Saxenda can hurt unborn babies, be sure to ask your physician if you're planning to become pregnant or are already pregnant. Since researchers are unsure if using liraglutide can affect nursing babies, you should also talk to your doctor if you are currently breast-feeding. Also, the US Food and Drug Administration has not approved Saxenda at this time for those who are under the age of 18.

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How to Take Saxenda

If you're new to taking Saxenda, then it's essential to know that this injection should be taken once each day. Also, be sure to read your prescription label to follow the manufacturer's directions. Sometimes, your physician may recommend a different dose.

In this case, only use as much Saxenda medication as prescribed by your doctor. In addition to this, make sure that you don't take Saxenda for longer than your doctor recommends as well. As mentioned above, do not mix Victoza and Saxenda at the same time. Even though they may contain similar active ingredients, they definitely shouldn't be taken together.

Not only that, but it is also crucial to read everything provided to you, including things such as:

• Patient information
• Medication guides
• Instruction sheets

Moving forward, Saxenda can be injected into your skin either in the morning or in the evening. Saxenda can even be taken with or without a meal.

First of all, you must learn how to take injectable medications in the comfort of your home. We strongly recommend that you avoid injecting yourself with this prescription if you don't have a general understanding of how to do it. When you are finished, be sure to dispose of your used syringes and needles properly too.

Made an injectable pen that is pre-filled, Saxenda must be used with the correct needle as well. If you aren't sure, you can always ask your physician to tell you where to inject Saxenda into your body. After the first injection, be sure to get yourself in a different area of your body every time. Also, avoid injecting yourself into the same body part more than once.

When to Avoid Taking Saxenda

Wondering when you should avoid taking Saxenda?

We suggest that you talk to your local pharmacist for new medication if your Saxendra has particles floating in it or has changed colors.

Other signs and symptoms to watch out for include the following:

• High blood sugar
• Increased urination or thirst
• Blurry vision
• Headaches
• Chronic fatigue

Besides this, your personal blood sugar level may be impacted by exercise, surgery, or illness. Not to mention that skipping meals, alcohol use, and stress may have an impact on your blood sugar levels as well. That's why we suggest that you talk to your doctor when you consider changing your medication or dose schedule.

More Precautions for Taking Saxenda

If you're considering taking Saxenda for the first time, be sure to follow these rules to stay safe:

• Only use disposable needles once each time
• Study all local and state laws regarding disposing of used syringes and needles
• Use disposable puncture-proof containers to store noodles
• Keep your puncture-proof container away from all pets and children
• Store unopened injectable pens in your refrigerator
• Avoid freezing Saxenda at all times
• Dispose of any frozen Saxenda medications
• Throw away unopened injectable pens if are expired

Remember that Saxenda is only a small part of your overall treatment process. In addition to taking Saxenda, your treatment protocol may include:

• Diet
• Exercise
• Weight control
• Regular blood sugar testing
• Other special medical care

After you've used Saxenda injectable pens, you should store them in your refrigerator or you can leave them out at "room temperature." Also, be sure to protect your injectable pens from sunlight, heat, moisture.

Use your dosage within one month and remove your needle before you store your injectable, Finally, make sure that the cap remains on when you're not using it.

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Saxenda Dose Guide

Please feel free to refer to the average dose levels of Saxenda for adults to maximize weight loss:

• The first week: Use 0.6 milligrams of medicine once each day
• The second week: Use 1.2 milligrams of medicine once each day
• The third week: Use 1.8 milligrams of medicine once each day
• The fourth week: Use 2.4 milligrams of medicine once each day
• The fifth week: Use 3 milligrams of medicine once each day

Once you've completed your initial Saxenda dosages with the guidance of a physician, you may be recommended to continue taking 3 milligrams of Saxenda as a "maintenance dose."

Saxenda Overdose Warnings

If you're concerned about taking your Saxenda medication correctly, we can help you out. For instance, we highly recommend that you take your missed dose as soon as you can recall skipping it. On the following day, take your next dose as you normally would. However, be sure to avoid taking an additional dose of this medication or double your dosage on the next day to counteract your skipped dose.

What should you do if you miss your dose for more than three days?

If that's the case, we suggest that you get in touch with your physician to discuss restarting your Saxenda treatment.

What to Do If You Overdose on Saxenda

If you feel like you may overdose from your Saxenda prescription, you must either call your local Poison Control hotline or seek medical attention right away.

What to Avoid While Taking Saxenda

The following should be avoided while taking your Saxenda prescription:

• Sharing injectable pens with others
• Sharing injectable cartridges with others
• Sharing injectable syringes with others

This is true even if you have changed your needle recently. That's because sharing your injectable device can allow these infections to spread from one patient to an additional patient.

Also, avoid using Saxenda with other appetite suppressants, diet pills, or weight loss products.

Saxenda Side Effects 

If you have an adverse reaction from using Saxenda, make sure that you seek medical attention if you have any of the following signs:

• Hive breakouts
• Increased heartbeats
• Enhanced dizziness
• Difficulty breathing
• Trouble swallowing
• Facial swelling
• Lip swelling
• Tongue swelling
• Throat swelling

In addition to this, be sure to talk to your doctor right away if you suffer from:

• Pounding or racing heartbeats
• Suicidal thoughts or sudden behavioral or mood changes
• Ongoing or severe diarrhea, vomiting, or nausea
• Thyroid tumor symptoms
• Gallbladder issues 
• Pancreatitis problems
• Hypoglycemia
• Kidney issues

Also, be prepared to experience the following side effects from taking Saxenda, which include the following symptoms:

• Stomach pain, vomiting, or nausea
• Enhanced heart rates
• Constipation or diarrhea
• Dizziness or headaches
• Chronic feelings of fatigue

For more information about potential side effects, please feel free to consult your primary physician or contact the US Food and Drug Administration.

Drugs That May Interact With Saxenda

In case you didn't know, taking Saxenda can potentially slow down your digestive tract, which means that your body may have a hard time absorbing other medications that you ingest orally.

Also, be sure to talk to your position about any medications that you are currently taking or that you would like to stop taking, including:

• All forms of insulin-related medications
• Oral diabetes medicines such as Glucovance, Micronase, DiaBeta, Duetact, Avandaryl, Amaryl, Metaglip, and Glucotrol
• Over-the-counter medications
• Prescription medications
• Natural supplements or vitamins
• Herbal medications

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How Much Will It Cost To Subscribe For Saxenda Refills?

The cost of Saxenda refills will depend on how many refills you need each month.

For instance:

• If you spend more than $500 per month, you'll save 20% on your order
• If you spend between $250 and $499 per month, you'll save 15% on your order
• If you spend between $100 and $249 per month, you'll save 10% on your order
• If you spent between $1 and $99 per month, you'll save 5% on your order

In addition to this, we offer free shipping to customers to place orders of more than $100.

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